Pubblicazioni di Fiscon Giulia

2023

Mezi Silvia, Pomati Giulia, Fiscon Giulia, Amirhassankhani Sasan, Zizzari Ilaria Grazia, Napoletano Chiara, Rughetti Aurelia, Rossi Ernesto, Schinzari Giovanni, Tortora Giampaolo, Lanzetta Gaetano, D'Amati Giulia, Nuti Marianna, Santini Daniele, Botticelli Andrea

A network approach to define the predictive role of immune profile on tumor response and toxicity of anti PD-1 single agent immunotherapy in patients with solid tumors. FRONTIERS IN IMMUNOLOGY 2023: -

Vitiello M., Mercatanti A., Podda M. S., Baldanzi C., Prantera A., Sarti S., Rizzo M., Salvetti A., Conte F., Fiscon G., Paci P., Poliseno L.

A Network of MicroRNAs and mRNAs Involved in Melanosome Maturation and Trafficking Defines the Lower Response of Pigmentable Melanoma Cells to Targeted Therapy. CANCERS 2023: -

Fiscon G., Conte F., Paci P.

A network-based algorithm for identifying drug repurposing opportunities for complex diseases. Convegno Nazionale di Bioingegneria 2023: -

Brunetti M., Paci P., Fiscon G.

A network-based bioinformatic analysis for identifying potential repurposable active molecules in different types of human cancers. Proceedings - 2023 2023 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2023 2023: 3626-3631

Taglino F., Cumbo F., Antognoli G., Arisi I., D’Onofrio M., Perazzoni F., Voyat R., Fiscon G., Conte F., Canevelli M., Bruno G., Mecocci P., Bertolazzi P.

An ontology-based approach for modelling and querying Alzheimer’s disease data. BMC MEDICAL INFORMATICS AND DECISION MAKING 2023: -

Conte F., Fiscon G., Paci P.

Bioinformatics analyses to identify molecular gene signatures associated with breast cancer phenotypes. Convegno Nazionale di Bioingegneria 2023: -

Fiscon G., Funari A., Paci P.

Circular RNA mediated gene regulation in human breast cancer: A bioinformatics analysis. PLOS ONE 2023: -

Zulian V., Fiscon G., Paci P., Garbuglia A. R.

Hepatitis B Virus and microRNAs: A Bioinformatics Approach. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2023: -

Botticelli Andrea, Cirillo Alessio, Pomati Giulia, Cortesi Enrico, Rossi Ernesto, Schinzari Giovanni, Tortora Giampaolo, Tomao Silverio, Fiscon Giulia, Farina Lorenzo, Scagnoli Simone, Pisegna Simona, Ciurluini Fabio, Chiavassa Antonella, Amirhassankhani Sasan, Ceccarelli Fulvia, Conti Fabrizio, Di Filippo Alessandra, Zizzari Ilaria Grazia, Napoletano Chiara, Rughetti Aurelia, Nuti Marianna, Mezi Silvia, Marchetti Paolo

Immune-related toxicity and soluble profile in patients affected by solid tumors: a network approach. CANCER IMMUNOLOGY, IMMUNOTHERAPY 2023: -

Zulian V., Garbuglia A. R., Fiscon G., Paci P.

Overview of bioinformatic tools to study viral infections. Proceedings - 2023 2023 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2023 2023: 3669-3675

Mezi Silvia, Botticelli Andrea, Scagnoli Simone, Pomati Giulia, Fiscon Giulia, De Galitiis Federica, Romana Di Pietro Francesca, Verkhovskaia Sofia, Amirhassankhani Sasan, Pisegna Simona, Gentile Giovanna, Simmaco Maurizio, Gohlke Bjoern, Preissner Robert, Marchetti Paolo

The impact of drug–drug Interactions on the toxicity profile of combined treatment with BRAF and MEK Inhibitors in patients with BRAF-mutated metastatic melanoma. CANCERS 2023: -

2022

Fiscon Giulia, Conte Federica, Farina Lorenzo, Paci Paola

A Comparison of Network-Based Methods for Drug Repurposing along with an Application to Human Complex Diseases. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2022: 1-15

Conte F., Sibilio P., Fiscon G., Paci P.

A Transcriptome- and Interactome-Based Analysis Identifies Repurposable Drugs for Human Breast Cancer Subtypes. SYMMETRY 2022: 2230-

Occhipinti M., Ferrara R., Imbimbo M., Simeon V., Fiscon G., Marchal C., Skoetz N., Viscardi G.

Adjuvant epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) for the treatment of people with resected stage I to III non-small-cell lung cancer and EGFR mutation. COCHRANE LIBRARY 2022: 1-13

Paci P., Fiscon G., Conte F., Wang R. -S., Handy D. E., Farina L., Loscalzo J.

Comprehensive network medicine-based drug repositioning via integration of therapeutic efficacy and side effects. NPJ SYSTEMS BIOLOGY AND APPLICATIONS 2022: 12-

Mezi Silvia, Pomati Giulia, Zizzari ILARIA GRAZIA, DI FILIPPO Alessandra, Cerbelli Bruna, Cirillo Alessio, Fiscon Giulia, Amirhassankhani Sasan, Valentini Valentino, DE VINCENTIIS Marco, Corsi Alessandro, DI GIOIA Cira Rosaria Tiziana, Tombolini Vincenzo, DELLA ROCCA Carlo, Polimeni Antonella, Nuti Marianna, Marchetti Paolo, Botticelli Andrea

Genomic and immune approach in platinum refractory HPV-negative head and neck squamous cell carcinoma patients treated with Immunotherapy: a novel combined profile. BIOMEDICINES 2022: -

Fiscon Giulia, Sibilio Pasquale, Funari Alessio, Conte Federica, Paci Paola

Identification of Potential Repurposable Drugs in Alzheimer’s Disease Exploiting a Bioinformatics Analysis. JOURNAL OF PERSONALIZED MEDICINE 2022: -

Tumino N., Besi F., Martini S., Di Pace A. L., Munari E., Quatrini L., Pelosi A., Fiore P. F., Fiscon G., Paci P., Scordamaglia F., Covesnon M. G., Bogina G., Mingari M. C., Moretta L., Vacca P.

Polymorphonuclear Myeloid-Derived Suppressor Cells Are Abundant in Peripheral Blood of Cancer Patients and Suppress Natural Killer Cell Anti-Tumor Activity. FRONTIERS IN IMMUNOLOGY 2022: 1-12

Amadio Susanna, Conte Federica, Esposito Giorgia, Fiscon Giulia, Paci Paola, Volonté Cinzia

Repurposing Histaminergic Drugs in Multiple Sclerosis. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2022: 1-16

Paci P., Fiscon G.

SPINNAKER: an R-based tool to highlight key RNA interactions in complex biological networks. BMC BIOINFORMATICS 2022: 1-13

Paci P., Fiscon G.

SWIMmeR: An R-based software to unveiling crucial nodes in complex biological networks. BIOINFORMATICS 2022: 586-588

2021

Conte F., Fiscon G., Sibilio P., Licursi V., Paci P.

An Overview of the computational models dealing with the regulatory ceRNA mechanism and ceRNA deregulation in cancer. Methods in Molecular Biology 2021: 149-164

Fiscon G., Salvadore F., Guarrasi V., Garbuglia A. R., Paci P.

Assessing the impact of data-driven limitations on tracing and forecasting the outbreak dynamics of COVID-19. COMPUTERS IN BIOLOGY AND MEDICINE 2021: 104657-

Fiscon G., Conte F., Amadio S., Volonte C., Paci P.

Drug Repurposing: A Network-based Approach to Amyotrophic Lateral Sclerosis. NEUROTHERAPEUTICS 2021: -

Paci P., Fiscon G., Conte F., Wang R. -S., Farina L., Loscalzo J.

Gene co-expression in the interactome: moving from correlation toward causation via an integrated approach to disease module discovery. NPJ SYSTEMS BIOLOGY AND APPLICATIONS 2021: -

Fiscon G., Pegoraro S., Conte F., Manfioletti G., Paci P.

Gene network analysis using SWIM reveals interplay between the transcription factor-encoding genes HMGA1, FOXM1, and MYBL2 in triple-negative breast cancer. FEBS LETTERS 2021: 1569-1586

Sibilio Pasquale, Bini Simone, Fiscon Giulia, Sponziello Marialuisa, Conte Federica, Pecce Valeria, Durante Cosimo, Paci Paola, Falcone Rosa, Norata Giuseppe Danilo, Farina Lorenzo, Verrienti Antonella

In silico drug repurposing in COVID-19. A network-based analysis. BIOMÉDECINE & PHARMACOTHÉRAPIE 2021: 1-10

Salvadore F., Fiscon G., Paci P.

Integro-differential approach for modeling the COVID-19 dynamics - Impact of confinement measures in Italy. COMPUTERS IN BIOLOGY AND MEDICINE 2021: 105013-

Fiscon G., Conte F., Farina L., Paci P.

SAveRUNNER: A network-based algorithm for drug repurposing and its application to COVID-19. PLOS COMPUTATIONAL BIOLOGY 2021: e1008686-

Fiscon G., Paci P.

SAveRUNNER: an R-based tool for drug repurposing. BMC BIOINFORMATICS 2021: -

Pecce V., Verrienti A., Fiscon G., Sponziello M., Conte F., Abballe L., Durante C., Farina L., Filetti S., Paci P.

The role of FOSL1 in stem-like cell reprogramming processes. SCIENTIFIC REPORTS 2021: 1-11

Bonanomi M., Salmistraro N., Fiscon G., Conte F., Paci P., Bravata V., Forte G. I., Volpari T., Scorza M., Mastroianni F., D'errico S., Avolio E., Piccialli G., Colangelo A. M., Vanoni M., Gaglio D., Alberghina L.

Transcriptomics and metabolomics integration reveals redox-dependent metabolic rewiring in breast cancer cells. CANCERS 2021: 5058-

2020

Conte F., Fiscon G., Licursi V., Bizzarri D., D'Anto T., Farina L., Paci P.

A paradigm shift in medicine: a comprehensive review of network-based approaches. BIOCHIMICA ET BIOPHYSICA ACTA. GENE REGULATORY MECHANISMS 2020: -

Paci Paola, Fiscon Giulia, Conte Federica, Licursi Valerio, Morrow Jarrett, Hersh Craig, Cho Michael, Castaldi Peter, Glass Kimberly, Silverman Edwin K., Farina Lorenzo

Integrated transcriptomic correlation network analysis identifies COPD molecular determinants. SCIENTIFIC REPORTS 2020: -

Silverman E. K., Schmidt H. H. H. W., Anastasiadou E., Altucci L., Angelini M., Badimon L., Balligand J. -L., Benincasa G., Capasso G., Conte F., Di Costanzo A., Farina L., Fiscon G., Gatto L., Gentili M., Loscalzo J., Marchese C., Napoli C., Paci P., Petti M., Quackenbush J., Tieri P., Viggiano D., Vilahur G., Glass K., Baumbach J.

Molecular networks in Network Medicine: Development and applications. WILEY INTERDISCIPLINARY REVIEWS. SYSTEMS BIOLOGY AND MEDICINE 2020: -

Panebianco Valeria, Pecoraro Martina, Fiscon Giulia, Paci Paola, Farina Lorenzo, Catalano Carlo

Prostate cancer screening research can benefit from network medicine: an emerging awareness. NPJ SYSTEMS BIOLOGY AND APPLICATIONS 2020: -

Maria Grimaldi Anna, Conte Federica, Pane Katia, Fiscon Giulia, Mirabelli Peppino, Baselice Simona, Giannatiempo Rosa, Messina Francesco, Franzese Monica, Salvatore Marco, Paci Paola, Mariarosaria Incoronato And

The new paradigm of Network Medicine to analyse breast cancer phenotypes. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020: -

2019

Fiscon G., Weitschek E., De Cola M. C., Felici G., Bertolazzi P.

An integrated approach based on EEG signals processing combined with supervised methods to classify Alzheimer's disease patients. Proceedings - 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018 2019: 2750-2752

Arisi I., Bertolazzi P., Cappelli E., Conte F., Cumbo F., Fiscon G., Sonnessa M., Taglino F.

An ontology-based approach to improve data querying and organization of Alzheimer's Disease data. Proceedings - 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018 2019: 2732-2734

Falcone Rosa, Conte Federica, Fiscon Giulia, Pecce Valeria, Sponziello Marialuisa, Durante Cosimo, Farina Lorenzo, Filetti Sebastiano, Paci Paola, Verrienti Antonella

BRAF V600E -mutant cancers display a variety of networks by SWIM analysis: prediction of vemurafenib clinical response. ENDOCRINE 2019: 406-413

Fiscon Giulia, Conte Federica, Farina Lorenzo, Pellegrini Marco, Russo Francesco, Paci Paola

Identification of Disease-miRNA networks across different cancer types using SWIM. MicroRNA Target Identication: Methods and Protocols 2019: 169-181

Licursi V., Conte F., Fiscon G., Paci P.

MIENTURNET: An interactive web tool for microRNA-target enrichment and network-based analysis. BMC BIOINFORMATICS 2019: 545-

Arisi I, D'Onofrio M, Brandi R, Sonnessa M, Campanelli A, Florio R, Sposato V, Malerba F, Cattaneo A, Mecocci P, Bruno G, Canevelli M, Tsolaki M, Pelteki N, Stocchi F, Vacca L, Fiscon G, Bertolazzi P

Mining clinical and laboratory data of neurodegenerative diseases by Machine Learning: transcriptomic biomarkers. 2018 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) 2019: 2735-2737

2018

Fiscon Giulia, Weitschek Emanuel, Cialini Alessio, Felici Giovanni, Bertolazzi Paola, De Salvo Simona, Bramanti Alessia, Bramanti Placido, De Cola Maria Cristina

Combining EEG signal processing with supervised methods for Alzheimer’s patients classification. BMC MEDICAL INFORMATICS AND DECISION MAKING 2018: 1-10

Fiscon G., Conte F., Licursi V., Nasi S., Paci P.

Computational identification of specific genes for glioblastoma stem-like cells identity. SCIENTIFIC REPORTS 2018: 1-10

Francesco Russo, Giulia Fiscon, Federica Conte, Milena Rizzo, Paci P, Marco Pellegrini

Interplay between long non-coding RNAs and microRNAs in cancer. Computational Cell Biology: Methods and Protocols 2018: 75-92

Fiscon Giulia, Conte Federica, Farina Lorenzo, Paci Paola

Network-based approaches to explore complex biological systems towards network medicine. GENES 2018: -

Falcone R., Paci P., Verrienti A., Fiscon G., Sponziello M., Conte F., Pecce V., Rosignolo F., Grani G., Lamartina L., Ramundo V., Durante C., Farina L., Filetti S.

Prediction of response to vemurafenib in BRAF V600E mutant cancers based on a network approach. ANNALS OF ONCOLOGY 2018: viii667-viii668